Pediatric high-grade gliomas (pHGG) are malignant and usually fatal central nervous system (CNS) WHO Grade 4 tumors.The majority of pHGG consist of diffuse Originals Loose Crop midline gliomas (DMG), H3.3 or H3.1 K27 altered, or diffuse hemispheric gliomas (DHG) (H3.3 G34-mutant).Due to diffuse tumor infiltration of eloquent brain areas, especially
Clostridium difficile is a Gram-positive, spore-forming bacterium, and major cause of nosocomial diarrhea.Related studies have identified numerous factors that influence virulence traits such as the production of the two primary toxins, toxin Refurbished Grinder A (TcdA) and toxin B (TcdB), as well as sporulation, motility, and biofilm formation.Ho
Following the proposal of Academic Council of Horticulture Faculty, the Senate of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca accepted nominee Professor Jules Janick for Doctor Honoris Causa award.The title was awarded in festive ceremony on September 30, 2010.Jules Janick, Professor at Purdue University has a long and d
Respiratory tract infections are a leading cause of morbidity and mortality in newborns, infants, and young children.These early life infections present a formidable immunologic challenge with a number of possibly conflicting goals: simultaneously eliminate the acute pathogen, preserve the primary Salt gas-exchange function of the lung parenchyma i
The novel nonsteroidal mineralocorticoid receptor (MR) antagonist finerenone holds promise to be safe and efficient in the treatment of patients with heart failure and/or chronic kidney disease.However, its effects on vascular function remain elusive.The aim of this study was to determine the functional effect of selective MR antagonism by finereno